Article

Novel Methods for Epistasis Detection in Genome-Wide Association Studies

2018-10-14

Abstract excerpt

More and more genome-wide association studies are being designed to uncover the full genetic basis of common diseases. Nonetheless, the resulting loci are often insufficient to fully recover the observed heritability. Epistasis, or gene-gene interaction, is one of many hypotheses put forward to explain this missing heritability. In the present work, we propose epiGWAS, a new approach for epistasis detection that i...

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Literature Corpus work: da4bf949-775c-50e4-a9fe-3dca64c2056c
DOI: 10.1101/442749

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