Article
A fast algorithm for learning epistatic genomic relationships.
AMIA ... Annual Symposium proceedings. AMIA Symposium - 13 Nov 2010
Jiang Xia, Neapolitan Richard E, Barmada M Michael, Visweswaran Shyam, Cooper Gregory F
Abstract excerpt
Genetic epidemiologists strive to determine the genetic profile of diseases. Epistasis is the interaction between two or more genes to affect phenotype. Due to the often non-linearity of the interaction, it is difficult to detect statistical patterns of epistasis. Combinatorial methods for detecting epistasis investigate a subset of combinations of genes without employing a search strategy. Therefore, they do not...
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