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Article

Novel methods for epistasis detection in genome-wide association studies.

PloS one - 1 Jan 2020

Slim Lotfi, Chatelain Clément, Azencott Chloé-Agathe, Vert Jean-Philippe

Abstract excerpt

More and more genome-wide association studies are being designed to uncover the full genetic basis of common diseases. Nonetheless, the resulting loci are often insufficient to fully recover the observed heritability. Epistasis, or gene-gene interaction, is one of many hypotheses put forward to explain this missing heritability. In the present work, we propose epiGWAS, a new approach for epistasis detection that...

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Identifiers

PMID: 33253293
DOI: 10.1371/journal.pone.0242927
PMCID: PMC7703915

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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