Article

A truncation mutant of adenomatous polyposis coli (APC) impairs apical cell extrusion through elevated epithelial tissue tension

2024-03-10

Abstract excerpt

<h4>ABSTRACT</h4> Tissue tension encompasses the mechanical forces exerted on solid tissues within animal bodies, originating from various sources such as cellular contractility, interactions with neighbouring cells and the extracellular matrix. Emerging evidence indicates that an imbalance in tissue tension can influence structural organisation, homeostasis and potentially contribute to disease. For instance, he...

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Literature Corpus work: da420484-c441-5f88-9c30-0eda58d129fd
DOI: 10.1101/2024.03.06.583801

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