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Article

p120-catenin controls contractility along the vertical axis of epithelial lateral membranes.

Journal of cell science - 1 Jan 2016

Yu Huapeng H, Dohn Michael R, Markham Nicholas O, Coffey Robert J, Reynolds Albert B

Abstract excerpt

In vertebrate epithelia, p120-catenin (hereafter referred to as p120; also known as CTNND1) mediates E-cadherin stability and suppression of RhoA. Genetic ablation of p120 in various epithelial tissues typically causes striking alterations in tissue function and morphology. Although these effects could very well involve p120's activity towards Rho, ascertaining the impact of this relationship has been complicated...

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Source

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Identifiers

PMID: 26585313
DOI: 10.1242/jcs.177550
PMCID: PMC4732297

Genes

CTNND1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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