Article

Mechanotransduction of strain regulates an invasive phenotype in newly transformed epithelial cells

2019-09-15

Abstract excerpt

Our organs and tissues are in constant motion, exposing epithelial cells to mechanical stretch. However, how these external forces impact cellular morphology, organization and dynamics in healthy and diseased tissues is still being elucidated. In several studies, we and others have shown how mechanical stresses and strains in the epithelium can modulate the dynamics and invasiveness of transformed cells. Carcinoma...

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Literature Corpus work: e8852870-9efe-5e03-8d2f-83f3ad3b746a
DOI: 10.1101/770487

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