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Article

A predictive model of intercellular tension and cell-matrix mechanical interactions in a multicellular geometry

2019-07-12

Abstract excerpt

Epithelial cells form continuous sheets of cells that exist in tensional homeostasis. Homeostasis is maintained through cell-to-cell adhesions that distribute tension and balance forces between cells and their underlying matrix. Disruption of tensional homeostasis can lead to Epithelial-Mesenchymal Transition (EMT), which is a transdifferentiation process in which epithelial cells adopt a mesenchymal phenotype, wh...

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Identifiers and source

Literature Corpus work
e20e60d1-4f3f-5c4f-aee2-5a9f5149d667
DOI
10.1101/701037
Open publication

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A predictive model of intercellular tension and cell-matrix mechanical interactions in a multicellular geometryDOI 10.1101/701037
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