Article

A dinucleotide tag-based parallel reporter gene assay method

2021-06-30

Abstract excerpt

The causal SNPs leading to increased cancer predisposition mainly function as gene regulatory elements, the evaluation of which largely rely on the parallel reporter gene assay system. However, the common DNA barcode-based parallel reporter gene assay systems are troubled with tag bias, mainly due to the tag nucleotide composition. Here we describe a versatile dinucleotide-tag reporter system (DiR) that enables pa...

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Literature Corpus work: da11d4a9-f497-57a3-8b9c-6df8befb92c7
DOI: 10.1101/2021.06.29.450267

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