Article

QuASAR-MPRA: Accurate allele-specific analysis for massively parallel reporter assays

2017-02-03

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Motivation</h4> The majority of the human genome is composed of non-coding regions containing regulatory elements such as enhancers, which are crucial for controlling gene expression. Many variants associated with complex traits are in these regions, and may disrupt gene regulatory sequences. Consequently, it is important to not only identify true enhancers but also to test if a variant wit...

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Literature Corpus work: 6ae3eb33-3006-59cc-94ae-4cacef116d2c
DOI: 10.1101/105627

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