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Article

Functional Screenings Identify Regulatory Variants Associated with Breast Cancer Susceptibility.

Current issues in molecular biology - 26 Oct 2021

Ren Naixia, Li Yingying, Xiong Yulong, Li Panfeng, Ren Yutian, Huang Qilai

Abstract excerpt

Genome-wide association studies (GWAS) have identified more than 2000 single nucleotide polymorphisms (SNPs) associated with breast cancer susceptibility, most of which are located in the non-coding region. However, the causal SNPs functioning as gene regulatory elements still remain largely undisclosed. Here, we applied a Dinucleotide Parallel Reporter sequencing (DiR-seq) assay to evaluate 288 breast cancer...

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Source

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Identifiers

PMID: 34889888
DOI: 10.3390/cimb43030124
PMCID: PMC8928974

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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