Article

Unbiased genome-scale identification of <i>cis</i> -regulatory modules in the human genome by GRAMc

2018-11-12

Abstract excerpt

Although significant advances have been made toward functionally identifying human regulatory elements, existing genome-scale reporter methods preferentially detect either enhancers or promoters. Here we develop GRAMc, a highly reproducible unbiased Genome-scale Reporter Assay Method for cis -regulatory modules (CRMs). GRAMc combines the versatility of traditional reporter constructs and the scalability of DNA ba...

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Literature Corpus work: 3245e1e7-52e2-5de2-b11e-500c1c662267
DOI: 10.1101/468405

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