Expressional profiling of prostate cancer risk SNPs at 11q13.5 identifies DGAT2 as a new target gene.

doi:10.1002/gcc.22368

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Article

Expressional profiling of prostate cancer risk SNPs at 11q13.5 identifies DGAT2 as a new target gene.

Genes, chromosomes & cancer - 1 Aug 2016

Nurminen Riikka, Rantapero Tommi, Wong Swee C, Fischer Daniel, Lehtonen Rainer, Tammela Teuvo L J, Nykter Matti, Visakorpi Tapio, Wahlfors Tiina, Schleutker Johanna

Abstract excerpt

A total of nine non-coding variants on 11q13.5 predispose men to prostate cancer (PrCa). rs200331695 within the EMSY intron is associated with aggressive PrCa and two high linkage disequilibrium (LD) groups of single-nucleotide polymorphisms (SNPs) in the intergenic region are associated with PrCa death. Here, the cis-effect of the SNPs on gene expression using expression quantitative trait loci analysis was...

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Identifiers

PMID: 27113481
DOI: 10.1002/gcc.22368

Genes

DGAT2
CAPN5
EMSY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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