Article

Germline variants associated with immunotherapy-related adverse events

2022-04-12

Abstract excerpt

Immune checkpoint inhibitors (ICIs) have yielded remarkable responses in patients across multiple cancer types, but often lead to immune related adverse events (irAEs). Although a germline cause for irAEs has been hypothesized, no systematic genome wide association study (GWAS) has been performed and no individual variants associated with the overall likelihood of developing irAEs have yet been identified. We carr...

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Literature Corpus work: da043ca9-501e-5cfb-8b08-a2aa57e80cfd
DOI: 10.1101/2022.04.10.22273627

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