Article

Phenotyping of fecal microbiota of Winnie, a rodent model of spontaneous chronic colitis, reveals specific metabolic, genotoxic, and pro-inflammatory properties

2022-05-06

Abstract excerpt

<title>Abstract</title> <italic>Winnie</italic>, a mouse carrying a missense mutation in the <italic>MUC2</italic> mucin gene, is a valuable model for inflammatory bowel disease (IBD) with signs and symptoms that have multiple similarities with those observed in patients with ulcerative colitis. MUC2 mucin is present in <italic>Winnie</italic>, but is not firmly compacted in a tight inner layer. Indeed, these...

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Literature Corpus work: d9a2b4cb-8c91-56f3-9686-9c6ef3f7f697
DOI: 10.21203/rs.3.rs-1404036/v1

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