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Article

Characterisation of colonic dysplasia-like epithelial atypia in murine colitis.

World journal of gastroenterology - 7 Oct 2016

Randall-Demllo Sarron, Fernando Ruchira, Brain Terry, Sohal Sukhwinder Singh, Cook Anthony L, Guven Nuri, Kunde Dale, Spring Kevin, Eri Rajaraman

Abstract excerpt

AIM: To determine if exacerbation of pre-existing chronic colitis in Winnie (Muc2 mutant) mice induces colonic dysplasia. METHODS: Winnie mice and C57BL6 as a genotype control, were administered 1% w/v dextran sulphate sodium (DSS) orally, followed by drinking water alone in week-long cycles for a total of three cycles. After the third cycle, mice were killed and colonic tissue collected for histological and...

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Source

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Identifiers

PMID: 27729740
DOI: 10.3748/wjg.v22.i37.8334
PMCID: PMC5055864

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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