Article

A missense mutation in <i>Muc2</i> promotes gut microbiome- and metabolome-dependent colitis-associated tumorigenesis

2025-06-03

Abstract excerpt

<h4>ABSTRACT</h4> Colitis-associated cancer (CAC) arises from a complex interplay between host and environmental factors, including the gut microbiome. Since ulcerative colitis (UC), a significant risk factor for CAC, is rising in prevalence worldwide, an integrative approach is essential to identify potential triggers linking inflammation to cancer. In the present study, we investigated the role of the gut micro...

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Literature Corpus work: fabea85c-e986-53e8-bf14-36dc9ebf8468
DOI: 10.1101/2025.05.31.657160

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