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Article

Gut microbiota shape the inflammatory response in mice with an epithelial defect

1 Jan 2021

Abstract excerpt

Intestinal epithelial cell endoplasmic reticulum (ER) stress has been implicated in intestinal inflammation. It remains unclear whether ER stress is an initiator of or a response to inflammation. Winnie mice, carrying a Muc2 gene mutation resulting in intestinal goblet cell ER stress, develop spontaneous colitis with a depleted mucus barrier and increased bacterial translocation. This study aims to determine...

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PMID: 33645438
DOI: 10.1080/19490976.2021.1887720

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Gut microbiota shape the inflammatory response in mice with an epithelial defectPMID 33645438Read ↗

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