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Article

The murine appendiceal microbiome is altered in spontaneous colitis and its pathological progression

1 Jun 2014

Abstract excerpt

BACKGROUND: Inflammatory bowel disease (comprising ulcerative colitis and Crohn's disease) is a multifactorial disease that is extensively associated with stool microbiome changes (dysbiosis). Appendicitis and appendectomy limits subsequent colitis, clinically, and in animal models. We wanted to examine how the appendiceal and stool microbiome fared in our spontaneous colitic Winnie (Muc2(-/-)) mice model....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25002910
DOI: 10.1186/1757-4749-6-25

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