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Microbiome- and Host Inflammasome-Targeting Inhibitor Nanoliogmers are Therapeutic in Murine Colitis Model

2024-02-20

Abstract excerpt

<h4>ABSTRACT</h4> Autoimmune and autoinflammatory diseases account for more than 80 chronic conditions affecting more than 24 million people in the US. Amongst these autoinflammatory diseases, non-infectious chronic inflammation of the gastrointestinal (GI) tract causes inflammatory bowel diseases (IBD), primarily Crohn’s and Ulcerative Colitis (UC). IBD is a complex disease, and one hypothesis is that these are...

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Literature Corpus work
f8d5fa38-175c-505a-876e-f5d726143162
DOI
10.1101/2024.02.20.581256
Open publication

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Microbiome- and Host Inflammasome-Targeting Inhibitor Nanoliogmers are Therapeutic in Murine Colitis ModelDOI 10.1101/2024.02.20.581256
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