Article

A collection of patient-derived intestinal organoid lines reveals epithelial pheno-types associated with genetic drivers of pediatric inflammatory bowel disease

2025-06-15

Abstract excerpt

Pediatric Inflammatory Bowel Disease (IBD) is a chronic condition characterized by per-sistent intestinal inflammation in children and adolescents. Despite a rising global incidence, the underlying causes and optimal management strategies for pediatric IBD are still not fully understood. Compared to adult IBD, pediatric IBD frequently presents with distinct disease phenotypes, and is more commonly linked to rare m...

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Literature Corpus work: 2640dc1e-e5f1-58dd-ac84-00a52eea7b1a
DOI: 10.1101/2025.06.11.659052

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