Article

SOX9 promotes stress-responsive transcription of VGF nerve growth factor inducible gene in kidney epithelial cells

2020-07-06

Abstract excerpt

Acute kidney injury (AKI) is a common clinical condition associated with diverse etiologies and abrupt loss of renal function. In patients with sepsis, rhabdomyolysis, cancer, as well as cardiovascular disorders, the underlying disease or associated therapeutic interventions can cause hypoxic, cytotoxic, and inflammatory insults to renal tubular epithelial cells (RTECs) resulting in the onset of AKI. To uncover st...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d93efad1-8b64-569f-9ab8-9ff06d8574f9
DOI: 10.1101/2020.07.06.189829

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SOX9 promotes stress-responsive transcription of VGF nerve growth factor inducible gene in kidney epithelial cellsDOI 10.1101/2020.07.06.189829Read

Androgens Drive SOX9 Upregulation in Injured Proximal Tubular CellsSemantic proximity Read

A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injurySemantic proximity Read

Interleukin Enhancer Binding Factor 2 (Ilf2) and Kidney Epithelial Stress ResilienceSemantic proximity Read

GDNF-engineered AMSC-derived exosomes attenuate renal interstitial fibrosis by promoting peritubular capillary regeneration via miR-29c-3p–IFN-γ–SIRT1 signalingSemantic proximity Read

Adipose-derived stem cell and their extracellular vesicles ameliorates immune function, and cardiac markers in experimental model of cardiorenal syndrome type III: TNF-α, IFN-γ and IL-10 cytokine production and their correlation with genotype.Semantic proximity Read

NFAT5 Confers Differential Expression in Innate Immune Cells vs. Renal Epithelial Cells in the Face of Osmotic StressSemantic proximity Read

Macula densa-specific NOS1 knockout determines susceptibility to ischemic acute kidney injury.Semantic proximity Read

The evolving role of TonEBP as an immunometabolic stress protein.Semantic proximity Read

Stress decreases host viral resistance and increases Covid susceptibility in embryonic stem cells.Semantic proximity Read

Stx2 induces differential gene expression by activating several pathways and disturbs circadian rhythm genes in the proximal tubuleSemantic proximity Read

HES1 contributes to high salt stress response as an enhancer of NFAT5-DNA bindingSemantic proximity Read

An EGFR-ERK-SOX9 Signaling Cascade Links Urothelial Development and Regeneration to CancerSemantic proximity Read