Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury

21 Apr 2020

Abstract excerpt

Renal tubular epithelial cells (RTECs) perform the essential function of maintaining the constancy of body fluid composition and volume. Toxic, inflammatory, or hypoxic-insults to RTECs can cause systemic fluid imbalance, electrolyte abnormalities and metabolic waste accumulation- manifesting as acute kidney injury (AKI), a common disorder associated with adverse long-term sequelae and high mortality. Here we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Kidney Injury Research
Share to Chronic Kidney Disease and Diabetes
Share to Renal and related cancers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32317630
DOI: 10.1038/s41467-020-15638-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injuryPMID 32317630Read ↗

Genome-wide association studies identify the role of caspase-9 in kidney diseaseSemantic proximity Read ↗

Single-nucleus Transcriptomics Reveals Precystic Dysfunction in Polycystic Kidney DiseaseSemantic proximity Read ↗

The single-cell transcriptomic landscape of early human diabetic nephropathySemantic proximity Read ↗

Multi-omics profiling of mouse polycystic kidney disease progression at a single cell resolutionSemantic proximity Read ↗

Single-Cell Profiling of AKI in a Murine Model Reveals Novel Transcriptional Signatures, Profibrotic Phenotype, and Epithelial-to-Stromal Crosstalk.Semantic proximity Read ↗

Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney diseaseSemantic proximity Read ↗

Epigenetic reprogramming driving successful and failed repair in acute kidney injurySemantic proximity Read ↗

The Single Cell Transcriptomic Landscape of Early Human Diabetic NephropathySemantic proximity Read ↗

Single Nucleus RNA Sequencing of Remnant Kidney Biopsies and Urine Cell RNA Sequencing Reveal Cell Specific Markers of Covid-19 Acute Kidney InjurySemantic proximity Read ↗

Epigenetic reprogramming driving successful and failed repair in acute kidney injurySemantic proximity Read ↗

Loss of RANBP3L leads to transformation of renal epithelial cells towards a renal clear cell carcinoma like phenotype.Semantic proximity Read ↗

Single-cell RNA sequencing reveals the transcriptomic landscape of kidneys in patients with ischemic acute kidney injurySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.