Article

Stx2 induces differential gene expression by activating several pathways and disturbs circadian rhythm genes in the proximal tubule

2021-06-11

Abstract excerpt

(1) <h4>Background</h4> Shiga toxin-producing Escherichia coli (STEC) causes proximal tubular defects in the kidney. However, factors altered by Shiga toxin (Stx) within the proximal tubules are yet to be shown. (2) <h4>Methods</h4> We determined Stx receptor Gb3 in murine and human kidneys and confirmed the receptor expression in the proximal tubules. Stx2-injected mouse kidney tissues and Stx2-treated human...

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Literature Corpus work: 06fdb9b1-83be-5217-8a8f-8eca6d38ec33
DOI: 10.1101/2021.06.11.448004

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