Article

Androgens Drive SOX9 Upregulation in Injured Proximal Tubular Cells

2025-10-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Sex influences susceptibility, recovery, and long-term outcomes after acute kidney injury (AKI) in humans. Rodent models have been invaluable for elucidating AKI mechanisms; however, most studies have focused on males, assuming direct applicability to females, an assumption that remains largely untested. In males, the transcription factor SOX9 regulates injury-associated p...

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Literature Corpus work: b6b7a18e-1880-55fd-adb2-367f9d7b28ca
DOI: 10.1101/2025.10.23.684153

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