Article

NFAT5 Confers Differential Expression in Innate Immune Cells vs. Renal Epithelial Cells in the Face of Osmotic Stress

2025-11-18

Abstract excerpt

The kidney develops an osmotic gradient, up to 1300 mOsm, to drive the reabsorption of water. However, this creates a harsh environment for renal epithelial and immune cells. These cells need to develop a survival mechanism to prevent against osmotic stress and maintain homeostasis in this harsh environment. N uclear F actor of A ctivated T Cells 5 (NFAT5, also known as Ton icity-Responsive E nhancer- B ind...

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Literature Corpus work: 491f07ed-1500-55dd-9479-23b5917ec667
DOI: 10.1101/2025.11.18.689108

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NFAT5 Confers Differential Expression in Innate Immune Cells vs. Renal Epithelial Cells in the Face of Osmotic StressDOI 10.1101/2025.11.18.689108Read

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