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Effect of Genetic Polymorphisms of CYP2C19 on the Steady-state Serum Concentrations of Valproic Acid in Chinese Han Patients With Schizophrenia

2020-07-20

Abstract excerpt

<title>Abstract</title> <p>Valproic acid is an anticonvulsant, which is also widely used for treating psychiatric disorders. Some clinical trials have demonstrated benefits of valproic acid augmentation therapy in schizophrenia. Interindividual variability in valproic acid dose and serum concentration may reflect functional consequences of genetic polymorphisms in genes encoding drug-metabolizing enzymes. The aim...

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Literature Corpus work
d8f94c9b-4521-5c66-b4f8-bcc05314c399
DOI
10.21203/rs.3.rs-38955/v1
Open publication

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Effect of Genetic Polymorphisms of CYP2C19 on the Steady-state Serum Concentrations of Valproic Acid in Chinese Han Patients With SchizophreniaDOI 10.21203/rs.3.rs-38955/v1
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