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The influence of cytochrome oxidase CYP2A6, CYP2B6, and CYP2C9 polymorphisms on the plasma concentrations of valproic acid in epileptic patients.

Clinical neurology and neurosurgery - 1 May 2010

Tan Lan, Yu Jin-Tai, Sun Yan-Ping, Ou Jiang-Rong, Song Jing-Hui, Yu Yang

Abstract excerpt

OBJECTIVES: To investigate influences of the functional polymorphisms of Cytochrome P450 isozymes 2A6 (CYP2A6), 2B6 (CYP2B6), and 2C9 (CYP2C9) on pharmacokinetics of VPA in vivo. PATIENTS AND METHODS: In the study, we analyzed the genotypes of CYP2A6, CYP2B6, and CYP2C9 and their contribution to...

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Identifiers

PMID: 20089352
DOI: 10.1016/j.clineuro.2010.01.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20089352-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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