Article

Long-read RNA sequencing identifies non-coding isoform switching as a regulator of cell fate

2025-02-23

Abstract excerpt

Development of long-read RNA sequencing technologies has paved the way to the exploration of RNA isoform diversity and its relevance in regulating cell fate. However, identifying new functional isoforms is still very difficult. Here, we leverage long-read RNA sequencing to study changes in isoforms during somatic cell reprogramming and identify novel isoforms occurring throughout cell state transitions. We demonst...

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Literature Corpus work: 23debe70-2ab3-554a-bf3d-ffb2b8aca708
DOI: 10.1101/2025.02.21.639524

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