Article

Sorafenib induces muscle wasting by disrupting the activity of distinct chromatin regulators

2024-01-04

Abstract excerpt

<h4>Summary</h4> Adverse effects of chemotherapies can outweigh the benefits in cancer patients. Various chemotherapeutics are linked to muscle wasting or cachexia, drastically reducing the chance of survivability of cancer patients. Insights into the molecular basis of chemotherapy-induced cachexia is an unmet need to improve the treatment strategies. Here, we investigated the tyrosine kinase inhibitor class of...

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Literature Corpus work: d8c34c5d-6f28-57fd-adf2-e6fbe97ba6ed
DOI: 10.1101/2024.01.04.574149

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