Article

Focal adhesion kinase inhibitor TAE226 combined with Sorafenib slows down hepatocellular carcinoma by multiple epigenetics effects

2021-09-16

Abstract excerpt

<h4>Background: </h4> Hepatocellular carcinoma (HCC) is one of the most common and lethal malignant tumours worldwide. Sorafenib (SOR) is one of the most effective single-drug systemic therapy against advanced HCC, but the identification of novel combination regimens for a continued improvement in overall survival is a big challenge. Recent studies highlighted the crucial role of focal adhesion kinase (FAK) in HCC...

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Literature Corpus work: d736a573-9daf-5fa1-b929-6e4c9bc39f0c
DOI: 10.21203/rs.3.rs-892488/v1

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