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Cancer-Associated Muscle Wasting—Candidate Mechanisms and Molecular Pathways

4 Dec 2020

Abstract excerpt

Excessive muscle loss is commonly observed in cancer patients and its association with poor prognosis has been well-established. Cancer-associated sarcopenia differs from age-related wasting in that it is not responsive to nutritional intervention and exercise. This is related to its unique pathogenesis, a result of diverse and interconnected mechanisms including inflammation, disordered metabolism, proteolysis...

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PMID: 33291708
DOI: 10.3390/ijms21239268

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