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Article

Cytoskeletal gene alterations linked to sorafenib resistance in hepatocellular carcinoma

2024-03-05

Abstract excerpt

<h4>Background: </h4> Although sorafenib has been consistently used as a first-line treatment for advanced hepatocellular carcinoma (HCC), most patients will develop resistance, and the mechanism of resistance to sorafenib needs further study. Methods Using KAS-seq technology, we obtained the ssDNA profiles within the whole genome range of 7721 cells treated with sorafenib for differential analysis. We then inter...

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Literature Corpus work
ca7c9ca9-b127-5c0f-8199-26cc0bd610da
DOI
10.21203/rs.3.rs-3996234/v1
Open publication

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Cytoskeletal gene alterations linked to sorafenib resistance in hepatocellular carcinomaDOI 10.21203/rs.3.rs-3996234/v1
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