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Article

Impact of SETD8/KMT5A Overexpression on Hepatocellular Carcinoma Progression and Prognosis

2025-11-13

Abstract excerpt

<h4>Background</h4> Hepatocellular carcinoma (HCC) has a poor prognosis due to its high recurrence rate, even after curative surgery. Epigenetic regulators play a critical role in cancer progression, and the histone methyltransferase SETD8/KMT5A has been reported to be overexpressed in various malignancies. This study aimed to elucidate the role of SETD8/KMT5A in HCC. <h4>Methods</h4> We investigated SETD8/KMT5A...

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Literature Corpus work
57992492-173f-520f-8f40-29bd3fb6521f
DOI
10.1101/2025.11.11.25340025
Open publication

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Impact of SETD8/KMT5A Overexpression on Hepatocellular Carcinoma Progression and PrognosisDOI 10.1101/2025.11.11.25340025
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