Article

bayesReact: Expression-coupled regulatory motif analysis detects microRNA activity in cancer and at the single cell level

2024-09-13

Abstract excerpt

Motivation: Regulatory constraints are crucial in maintaining tissue and cell integrity, and play important roles during developmental processes and environmental responses. Yet many regulatory mechanisms remain unobserved at the single-cell level and statistical inference may, in some cases, help elucidate their condition-specific activity and perturbation during disease progression. <h4>Results:</h4> We introduc...

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Literature Corpus work: d86acf5a-4816-5ef9-8c47-9a88ab38428a
DOI: 10.1101/2024.09.10.612047

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