Article

An information content principle explains regulatory patterns of gene expression across human tissues

2026-02-19

Abstract excerpt

Gene expression patterns range from broadly expressed housekeeping genes to highly tissue-specific ones. Notably, many genes exhibit intermediate specificity, characterized by elevated expression in some tissues while low or absent in others. Understanding how regulatory demands scale with tissue specificity offers a valuable opportunity to uncover fundamental principles of genome regulation. By analyzing cis -re...

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Literature Corpus work: b3b293e6-36dc-5071-a1c2-5ab4ca82fd06
DOI: 10.64898/2026.02.19.706555

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