Article

Large-scale, interpretable gene regulatory network inference through biologically informed matrix factorization

2026-07-16

Abstract excerpt

Gene regulatory networks (GRNs) provide a mechanistic framework for understanding how transcription factors coordinate gene expression to establish cellular identity and phenotype. Methods that integrate gene expression with motif-derived regulatory priors and other sources of biological information have substantially advanced gene regulatory network inference by reconstructing condition-specific regulatory archit...

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Literature Corpus work: d8ed70b0-4a4a-562f-8eaa-dabae9cb27f6
DOI: 10.64898/2026.07.15.738791

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