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Article

Characterization of WWOX Expression and Function in Canine Mast Cell Tumors and Malignant Mast Cell Lines

2020-05-28

Abstract excerpt

<title>Abstract</title> <p>Background The WW domain-containing oxidoreductase (WWOX) tumor suppressor gene is frequently lost in solid and hematopoietic malignancies in humans. Dysregulation of WWOX has been implicated as playing a key role in tumor cell survival, DNA damage repair, and genomic stability. The purpose of this study was to characterize WWOX expression in spontaneous canine mast cell tumors (MCTs)...

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Literature Corpus work
d85ccde9-3bb1-5320-9194-6dc6e3dc6f4e
DOI
10.21203/rs.3.rs-25520/v1
Open publication

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