WWOX promotes osteosarcoma development via upregulation of Myc

Abstract excerpt

<title>Abstract</title> <p>Osteosarcoma (OS) is an aggressive bone tumor that primarily affects children and adolescents. This malignant tumor is highly aggressive, associated with poor clinical outcomes, and metastasizes mainly to the lungs. Due to its rarity and biological heterogeneity, limited studies of its molecular basis exist, thus hindering the development of effective therapies. WW domain-containing oxi...

Topics

Open a Topic to create a Post that cites this publication.

• Genetics and Neurodevelopmental Disorders
• Genomics
• High-Throughput Nucleotide Sequencing
• Inheritance Patterns
• Models, Biological
• Osteosarcoma
• Peptidase Inhibition and Analysis
• RNA modifications and cancer

Identifiers and source

Literature Corpus work

45f6b60a-19c9-5042-82eb-502d34d506c0

DOI

10.21203/rs.3.rs-3411738/v1