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WWOX promotes osteosarcoma development via upregulation of Myc

5 Jan 2024

Abstract excerpt

Osteosarcoma is an aggressive bone tumor that primarily affects children and adolescents. This malignancy is highly aggressive, associated with poor clinical outcomes, and primarily metastasizes to the lungs. Due to its rarity and biological heterogeneity, limited studies on its molecular basis exist, hindering the development of effective therapies. The WW domain-containing oxidoreductase (WWOX) is frequently...

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PMID: 38182577
DOI: 10.1038/s41419-023-06378-8

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