Article
c-KIT messenger RNA and protein expression and mutations in canine cutaneous mast cell tumors: correlations with post-surgical prognosis.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc - 1 Jan 2012
Giantin Mery, Vascellari Marta, Morello Emanuela Maria, Capello Katia, Vercelli Antonella, Granato Anna, Lopparelli Rosa Maria, Nassuato Chiara, Carminato Antonio, Martano Marina, Mutinelli Franco, Dacasto Mauro
Abstract excerpt
Cutaneous mast cell tumors (MCTs) are among the most common neoplasms in dogs and show a highly variable biologic behavior. Histological grading, cell proliferation markers, and KIT immunohistochemistry are typically used to predict post-surgical prognosis. In the present study, c-KIT messenger RNA (mRNA) expression was measured in canine MCTs and its relationship with tumor grade, immunohistochemical staining...
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