Article

From Lipid Dynamics to Precision Predictions: A New Approach Methodology for Precision Modeling of Phosphoinositide Signaling

2025-07-07

Abstract excerpt

Precision medicine requires models that can translate rich molecular measurements into individualized predictions of biological response. This challenge is particularly acute for phosphoinositide signaling disorders that often exhibit cell-type-specific responses to identical genetic or pharmacological perturbations. Here, we develop a New Approach Methodology (NAM) demonstrating that basal phosphoinositide pool c...

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Literature Corpus work: d7e6b5b3-d43d-5c4d-b13f-79b23447bd3d
DOI: 10.1101/2025.07.03.663046

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