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Article

Information transfer by leaky, heterogeneous, protein kinase signaling systems.

Proceedings of the National Academy of Sciences of the United States of America - 21 Jan 2014

Voliotis Margaritis, Perrett Rebecca M, McWilliams Chris, McArdle Craig A, Bowsher Clive G

Abstract excerpt

Cells must sense extracellular signals and transfer the information contained about their environment reliably to make appropriate decisions. To perform these tasks, cells use signal transduction networks that are subject to various sources of noise. Here, we study the effects on information transfer of two particular types of noise: basal (leaky) network activity and cell-to-cell variability in the componentry...

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Identifiers

PMID: 24395805
DOI: 10.1073/pnas.1314446111
PMCID: PMC3903221

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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