Article

A model of the PI cycle reveals the regulating roles of lipid-binding proteins and pitfalls of using mosaic biological data

2020-05-26

Abstract excerpt

The phosphatidylinositol (PI) cycle is central to eukaryotic cell signaling. Its complexity, due to the number of reactions and lipid and inositol phosphate intermediates involved makes it difficult to analyze experimentally. Computational modelling approaches are seen as a way forward to elucidate complex biological regulatory mechanisms when this cannot be achieved solely through experimental approaches. Whilst...

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Literature Corpus work: fcc92d37-fdfa-5628-b787-965c2aa1eef8
DOI: 10.1101/2020.05.26.116251

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