Article

Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution

2018-12-19

Abstract excerpt

Direct comparisons of human and non-human primate brain tissue have the potential to reveal molecular pathways underlying remarkable specializations of the human brain. However, chimpanzee tissue is largely inaccessible during neocortical neurogenesis when differences in brain size first appear. To identify human-specific features of cortical development, we leveraged recent innovations that permit generating plur...

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Literature Corpus work: d7e0adbb-9322-5a58-aad8-ff9aebf649d7
DOI: 10.1101/500934

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