Article
Primate cell fusion disentangles gene regulatory divergence in neurodevelopment.
Nature - 1 Apr 2021
Agoglia Rachel M, Sun Danqiong, Birey Fikri, Yoon Se-Jin, Miura Yuki, Sabatini Karen, Pașca Sergiu P, Fraser Hunter B
Abstract excerpt
Among primates, humans display a unique trajectory of development that is responsible for the many traits specific to our species. However, the inaccessibility of primary human and chimpanzee tissues has limited our ability to study human evolution. Comparative in vitro approaches using primate-derived induced pluripotent stem cells have begun to reveal species differences on the cellular and molecular levels1,2....
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