Article

Single-cell multiomics atlas of organoid development uncovers longitudinal molecular programs of cellular diversification of the human cerebral cortex

2022-03-19

Abstract excerpt

Realizing the full utility of brain organoids as experimental systems to study human cortical development requires understanding whether organoids replicate the cellular and molecular events of this complex process precisely, reproducibly, and with fidelity to the embryo. Here we present a comprehensive single-cell transcriptomic, epigenetic, and spatial atlas of human cortical organoid development, comprising ove...

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Literature Corpus work: 1c7d645a-9f19-544c-900b-426bd076dd19
DOI: 10.1101/2022.03.17.484798

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Single-cell multiomics atlas of organoid development uncovers longitudinal molecular programs of cellular diversification of the human cerebral cortexDOI 10.1101/2022.03.17.484798Read

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