Article

Brain regional identity and cell type specificity landscape of human cortical organoid models

2022-02-17

Abstract excerpt

<h4>ABSTRACT</h4> In vitro models of corticogenesis using mouse and human pluripotent stem cells (PSC) have greatly improved our understanding of human brain development and disease. Among these, 3D cortical organoid systems are able to recapitulate some aspects of in vivo cytoarchitecture of the developing cortex. Here, we tested three cortical organoid protocols for brain regional identity, cell type-specific...

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Literature Corpus work: 6fc8aa37-ad48-5d1e-9bdf-b44859b3bdf5
DOI: 10.1101/2022.02.17.480833

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