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A structural mean modelling Mendelian randomization approach to investigate the lifecourse effect of adiposity: applied and methodological considerations

2024-03-28

Abstract excerpt

The application of a lifecourse approach to genetic epidemiology is key to better understanding causal effects of adversities on health outcomes over time. For some time-varying phenotypes, it has been shown that genetic effects may have differential importance in the development of an exposure at different periods in the lifecourse. Mendelian randomization (MR) is a technique that uses genetic variation to addres...

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Literature Corpus work
d7cd6f2d-26a2-5af7-b19c-785203d78a44
DOI
10.1101/2024.03.27.24304961
Open publication

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A structural mean modelling Mendelian randomization approach to investigate the lifecourse effect of adiposity: applied and methodological considerationsDOI 10.1101/2024.03.27.24304961
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