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Disentangling the direct and indirect effects of childhood adiposity on type 1 diabetes and immune-associated diseases: a multivariable Mendelian randomization study

2021-04-20

Abstract excerpt

<h4>Background</h4> The rising prevalence of childhood obesity has been postulated as an explanation for the increasing rate of individuals diagnosed with type 1 diabetes (T1D). However, robust causal evidence supporting this claim has been extremely challenging to uncover, particularly given the typical early onset of T1D. <h4>Methods</h4> In this study, we used genetic variation to separate the direct effect of...

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Literature Corpus work
a9210ee0-52b8-5f81-a8c1-de659fe0cc88
DOI
10.1101/2021.04.19.21255222
Open publication

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Disentangling the direct and indirect effects of childhood adiposity on type 1 diabetes and immune-associated diseases: a multivariable Mendelian randomization studyDOI 10.1101/2021.04.19.21255222
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