Article
Adiposity may confound the association between vitamin D and disease risk - a lifecourse Mendelian randomization study.
eLife - 8 Aug 2022
Richardson Tom G, Power Grace M, Davey Smith George
Abstract excerpt
Background: Vitamin D supplements are widely prescribed to help reduce disease risk. However, this strategy is based on findings using conventional epidemiological methods which are prone to confounding and reverse causation. Methods: In this short report, we leveraged genetic variants which differentially influence body size during childhood and adulthood within a multivariable Mendelian randomization (MR)...
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